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Stroke Drug Antidote

Leah Sarich | posted Monday, Jun 13th, 2016

strokeantidote

June is stroke month. I’ve already blogged about the symptoms of stroke so people can get the care they need as quickly as possible. Today, we’re looking at a new medication that can help one group of patients at risk of stroke. People with atrial fibrillation or an irregular heart beat are at increased risk for stroke. The Department Head of Emergency Medicine at the University of Calgary, Dr. Eddy Lang, says there are about 350 thousand Canadians living with atrial fibrillation which makes them 3 to  5 times more likely to have a stroke.

Dr. Lang explains when the heart is not pumping properly a blood clot can form and that clot can travel to the brain causing a stroke. For this reason, many of these patients are on a blood thinning medication to reduce the risk of that stroke occurring. But these blood thinners leave patients at risk in an emergency situation. Dr. Lang says for example, if a patient has a stomach ulcer that starts to bleed or is in an accident that requires surgery, it make be too risky for the patient to undergo surgery for fear of bleeding out. Dr. Lang says the blood thinner is a double edged sword. It does reduce a patient’s risk of stroke, but it also leaves them at risk of bleeding in an emergency. Until now.

Dr. Lang says Health Canada has just approved an antidote to one of these blood thinners. The antidote, made from human antibodies, effectively and safely neutralizes the effects of the blood thinner allowing patients to get the care they need. Dr. Lang says it turns patients into someone who had never been on a blood thinner within a matter of hours, allowing that patient to perhaps have surgery if required or avoid the OR altogether. Then, once a patient is stabilized, they can return to taking their blood thinner to reduce their risk of stroke. Dr. Lang says this antidote is in widespread use in the US and should be available in Calgary in the next couple of weeks.

Dr. Lang encourages anyone on a blood thinner to prevent stroke to talk to their family doctor about their options so they’re prepared in an emergency situation.

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